Hyperbaric Oxygen Therapy
Iyperbaric medicine, also referred to as hyperbaric oxygen therapy (HBOT),
involves the medical application of oxygen at levels higher than atmospheric
pressure. The necessary equipment includes a pressure chamber, which may be
constructed rigidly or flexibly, and a method for administering 100% oxygen.
Trained personnel operate the equipment according to a predetermined
schedule, monitoring the patient's condition and making adjustments as
necessary.
While HBOT was initially developed for treating decompression sickness, it
has proven effective for conditions like gas gangrene and carbon monoxide
poisoning. Although research has explored its potential benefits for
conditions such as cerebral palsy and multiple sclerosis, significant
evidence remains lacking.
HBOT employs several therapeutic principles:
- Increased overall pressure is beneficial for treating decompression
sickness and air embolism.
- In many cases, HBOT's therapeutic effect stems from significantly raising
the partial pressure of oxygen in the body's tissues, surpassing levels
achievable with pure oxygen at normal atmospheric pressure.
- Another benefit is the enhanced oxygen transport capacity of the blood.
While oxygen transport is typically limited by the oxygen-binding capacity
of hemoglobin in red blood cells, HBOT stimulates increased oxygen transport
via blood plasma.
- Recent evidence suggests that HBOT exposure mobilizes stem/progenitor
cells from the bone marrow through a nitric oxide-dependent mechanism,
potentially aiding in the recovery of damaged organs and tissues.
Originally developed for treating diving-related disorders like
decompression sickness and gas embolism, HBOT reduces the size of gas
bubbles in tissues and enhances blood flow to affected areas. The high
oxygen concentrations help sustain oxygen-deprived tissues and facilitate
the removal of nitrogen from bubbles, making them smaller until they consist
solely of oxygen, which is reabsorbed by the body. Following bubble
elimination, pressure is gradually returned to atmospheric levels.
Patients may experience discomfort in their ears due to pressure
differences, alleviated by techniques like the Valsalva maneuver or "jaw
wiggling." As pressure increases, mist and warmth may develop within the
chamber, potentially causing ear drum rupture and severe pain.
To reduce pressure, a valve is opened, allowing air to exit the chamber. As
pressure decreases, ear squeaking may occur as pressure inside the ear
normalizes with the chamber. Temperature within the chamber decreases
accordingly, with pressurization and depressurization rates adjusted based
on individual patient needs.
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